Lorlagen 100 Mg
Lorlagen (Lorlatinib), generic Lorbrena is a prescription medicine that is used to treat metastatic non-small cell lung cancer in patients who have a certain type of abnormal anaplastic lymphoma kinase (ALK) gene. Lorlatinib is used in patients who have already received alectinib, ceritinib, or both crizotinib and at least 1 other medicine to treat NSCLC that is caused by the ALK gene. Lorlagen is manufactured by General Pharmaceuticals Ltd. in Bangladesh.
Description
Non-small Cell Lung Cancer Indications Indicated for patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) whose disease has progressed on the following Crizotinib and at least 1 other ALK inhibitor, OR Alectinib or ceritinib as first ALK inhibitor therapy 100 mg PO qDay with or without food Continue until disease progression or unacceptable toxicity Hepatic impairment Mild (total bilirubin ?ULN with AST >ULN or total bilirubin >1-1.5x ULN with any AST): No dose adjustment necessary Moderate or severe: Recommended dose not established
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